Current & Forthcoming Publications

Peer-reviewed publications by DMETRE team members

  1. Rowe S, Karkhaneh Z, MacDonald I, Chambers T, Amjad S, Osornio-Vargas A, Chari R, Kumar M, Ospina MB. Systematic Review of the Measurement Properties of Indices of Prenatal Care Utilization. BMC Pregnancy and Childbirth 2020. doi: 10.1186/s12884-020-2822-5.
  2. Voaklander B, Rowe S, Sanni O, Campbell S, Ulrich D, Ospina MB. The prevalence of diabetes in pregnancy among Indigenous women: a systematic review and meta-analysis. Accepted for publication at Lancet Global Health 2020. LANGLH-D-19-00983.
  3. Michas M, Deuchar L, Leigh R, Bhutani M, Rowe BH, Stickland MK, Ospina MB, for the COPD PRIHS-2 Group. Factors influencing the implementation and uptake of a discharge care bundle for patients with acute exacerbation of chronic obstructive pulmonary disease: a qualitative focus group study. Implementation Science Communications 2020. 1:3. dorg/10.1186/s43058-020-00017-5.
  4. Ospina MB, Osornio-Vargas A, Nielsen CC, Crawford S, Kumar M, Aziz K, Serrano-Lomelin J. Socioeconomic gradients of adverse birth outcomes and related maternal factors in rural and urban Alberta, Canada: a concentration index approach. BMJ OpenFeb 2;10(1):e033296. 10:doi: 10.1136/bmjopen-2019-033296
  5. Belon AP, Serrano-Lomelin J, Nykiforuk C, Hicks A, Crawford S, Bakal J, Ospina MB. Health gradients in emergency department visits and hospitalizations for pediatric respiratory diseases. Paediatr Perinatal Epidemiol Feb 3.  DOI:10.1111/ppe.12639.
  6. Ospina MB, Serrano-Lomelin J, Amjad S, Hicks A, Giesbrecht G. Latent factors of adverse childhood experiences and adult onset asthma. J Dev Orig Health Dis2020 Jan 15:1-8. doi:
  7. Craincross ZF, Chaput K, McMorris C, Ospina MB, Metcalfe A. Roles of the underlying cause of delivery and gestational age on long-term child health. Paediatr Perinatal Epidemiol Feb 11 DOI:10.1111/ppe.12648.
  8. Frenette P, Crawford S, Schulz J, Ospina MB. Author response: the type of episiotomy should be studied carefully. J Obstetric Gynaecol Canada41(11):1549-50.
  9. Amjad S, Chandra S, Osornio-Vargas A, Voaklander D, Ospina MB. Maternal area of residence, socioeconomic status and risk of adverse maternal and birth outcomes in adolescent mothers. J Obstet Gynaecol Canada2019 Apr 29. pii: S1701-2163(19)30244-0. [Epub ahead of print].
  10. Black K, Chambers T, MacDonald I, Ospina MB. Postpartum mental health disorders in Indigenous women: a systematic review and meta-analysis. J Obstet Gynaecol Canada2019Apr 10. pii: S1701-2163(19)30080-5. doi: 10.1016/j.jogc.2019.02.009. [Epub ahead of print].
  11. Frenette P, Crawford S, Schulz J, Ospina MB. Impact of episiotomy during operative vaginal delivery on obstetrical anal sphincter injuries. J Obstet Gynaecol Canada2019 Apr 16. pii: S1701-2163(19)30091-X. doi: 10.1016/j.jogc.2019.02.016. [Epub ahead of print].
  12. Ahmed H, Ospina M, Sideri K, Vliagoftis H. Retrospective analysis of aeroallergen's sensitization patterns in Northern Alberta. Allergy, Asthma Clin Immunol2019; 15(6):
  13. Kozyrskyj AL, Bourque SL, Ospina MB. Microbiota be nimble. EBioMedicine2019; 39:21-22. doi: 10.1016/j.ebiom.2018.11.058
  14. Amjad S, MacDonald I, Chambers T, Osornio-Vargas A, Chandra S, Voaklander D, Ospina MB. Social determinants of health and adverse maternal and birth outcomes in adolescent pregnancies: a systematic review and meta-analysis. Paediatr Perinat Epidemiol. 2019;33(1):88-99.
  15. Villa-Roel C, Ospina M, Majumdar SR, Couperthwaite S, Rawe E, Nikel T, Rowe BH. Engaging patients and primary care providers in the design of novel opinion leader based interventions for acute asthma in the emergency department: a mixed methods study. BMC Health Serv Res. 2018; 18(1):789.
  16. Pendharkar S, Ospina M, Southern D, Hirani N, Graham J, Faris P, Bhutani M, Leigh R, Mody C. Stickland M. Effectiveness of a standardized electronic admission order set for acute exacerbation of chronic obstructive pulmonary disease. BMC Respir Med2018;18:93.
  17. Ospina MB, Michas M, Deuchar L, Leigh R, Bhutani M, Rowe BH, Marciniuk D, Goodridge D, Dechman G, Bourbeau J, Balter M, Camp P, Hernandez P, Goldstein RS, Stickland MK, PhD, for the COPD PRIHS-2 Group. Development of a patient-centered, evidence- and consensus-based discharge care bundle for patients with acute exacerbation of chronic obstructive pulmonary disease. BMJ Open Respir Res2018; 5(1):e000265.
  18. Rosychuk RJ, Ospina M, Zhang J, Leigh R, Cave A, Rowe BH. Sex differences in outcomes after discharge from the emergency department for asthma in Alberta, Canada: a population-based study. J Asthma2018 Aug 55(8):817-25.
  19. Villa-Roel C, Voaklander B, Ospina MB, Nikel T, Campbell S, Rowe BH. Effectiveness of written asthma action plans for acute asthma: a systematic review. J Asthma2017Apr 28:1-8. doi: 10.1080/02770903.2017.1318142.
  20. Ospina MB, Mrklas K, Deuchar L, Rowe BH, Leigh R, Bhutani M, Stickland M. A systematic review of the effectiveness of discharge care bundles for patients with chronic obstructive pulmonary disease.Thorax 2017,72(1):31-39. doi: 10.1136/thoraxjnl-2016-208820. (Editor’s choice).
  21. Moe J, Kirkland SK, Rawe E, Ospina MB, Vandermeer B, Campbell S, Rowe BH. Effectiveness of interventions to decrease emergency department visits by adult frequent users: A systematic review. Acad Emerg Med2017, 26(1):40-52 (Editor-in-Chief Pick).
  22. Ospina MB, Rowe BH, Voaklander D, Sentilselvan A, Stickland MK, King M. Emergency department visits after diagnosed chronic obstructive pulmonary disease in Aboriginal People in Alberta, Canada. CJEM2016 Nov,18(6):420-8.
  23. Rodriguez-Villamizar LA, Berney C, Villa-Roel C,Ospina MB, Osornio-Vargas A, Rowe BH. The role of socioeconomic position as an effect-modifier of the association between outdoor air pollution and children’s asthma exacerbations: An equity-focused systematic review. Rev Environ Health2016 Sep 1, 31(3):297-309.
  24. Ling L, Ospina MB, Sideri K, Vliagoftis H. Retrospective analysis on the agreement between skin prick test and serum food specific IgE antibody results in adults with suspected food allergy. Allergy, Asthma and Clinical Immunology2016,20:30. Doi 10.1186/s13223-016-0136-y


Registered systematic review protocols

  1. Pihelgas A, Jain V, Ospina M, Prior A. Decreasing insulin requirements during the third trimester amongst women with insulin dependent gestational and pregestational diabetes and its association to maternal-fetal outcomes: a systematic review. PROSPERO 2019 CRD 42019142976.
  2. Lau S, Marani S, Desai V, Sanni O, Dennett L, Walter J, Ospina M, Kozyrskyj A. Cesarean section delivery and neurodevelopment: systematic evidence for variation by birth events and impairment phenotype. PROSPERO 2019 CRD 42019137158.
  3. Fellus S, Kaul P, Ospina M, Chari R, Kung J. A systematic review of the impact of social and economic determinants of health and the occurrence of preeclampsia. PROSPERO 2019 CRD 42019140087.
  4. Belon AP, Ospina M, Seabrook J, Sullivan H, Dennett L. The association between maternal cannabis exposure during pregnancy and/or breastfeeding and physical and socio-behavioural health outcomes during prenatal period, infancy (0-2 years old) and early childhood (3-5 years old): an overview of systematic reviews and meta-analyses. PROSPERO 2019 CRD 42019139859.
  5. Sullivan H, Ospina M, Chari R, Hodgins S, Amjad S, Campbell S. Exposure to synthetic oxytocin during labour and birth and risk of postpartum depression and anxiety: a systematic review. PROSPERO 2019 CRD 42019135359.
  6. Ospina M, Desai V, Lau S, Sanni O, Walter J, Kozyrskyj A, Dennet L. A systematic review of the effectiveness of prebiotic, probiotic, and synbyotic supplementation in pregnancy to reduce the risk of maternal mental health disorders in the perinatal period. PROSPERO 2019 CRD 42019137158.
  7. Ospina MB, Bourque S, Chambers T, Rowe S, Li JH, Woodman A. A systematic review of the association between maternal iron status and anemia during pregnancy, and iron status and anemia in neonates and infants. PROSPERO 2018. CRD 42018093094.
  8. Moore L, Voaklander B, Yeung R, Ryan E, Chojecki D, Kaul P, Ospina M. Using antepartum oral glucose tolerance test levels to predict risk of future type 2 diabetes mellitus among women with gestational diabetes: a systematic review and meta-analysis. PROSPERO 2018 CRD 42018100316.
  9. Ospina MB, Osornio-Vargas AR, Rowe SR, Chojecki D. Identifying the association between wildfire smoke exposure and adverse birth outcomes: a systematic review. PROSPERO 2018 CRD 42018094103.
  10. Amjad S, Ganz F, Bajpai S, Ospina M, Armijo-Olivo S. Effectiveness of Procarbazine, Lomustine, and Vincristine (PCV) Chemotherapy Compared to Temozolomide (TMZ) for grade II and III Gliomas: a systematic review. PROSPERO 2018 CRD 42018080743.
  11. Ospina M, Rowe S, Karkhaneh Z, MacDonald I, Chambers T, Chari R, Kumar M, Chandra S, Osornio-Vargas A. A systematic review of the measurement properties of indices of prenatal care adequacy. PROSPERO 2017. CRD Available from:
  12. Amjad S, Ospina M, Voaklander D, Chandra S, Rowe S, Karkhaneh Z, MacDonald I. The impact of social determinants of health on adverse maternal and birth outcomes in adolescent pregnancies. PROSPERO 2017 CRD42017068749.
  13. Ospina M, Karkhaneh Z, Rowe S, Chambers T, Osornio-Vargas A, MacDonald I. Adverse birth outcomes and the development of respiratory disease in infancy, childhood and adulthood: a systematic review. PROSPERO 2017 CRD
  14. Ospina M, Karkhaneh Z, Rowe S, MacDonald I, Chambers T, Osornio-Vargas A. Overview of systematic reviews and meta-analyses of the relationship between birth and infant growth characteristics and respiratory outcomes in infancy, childhood, and adulthood. PROSPERO 2017 CRD42017072745.


We are located at the Heritage Medical Research Centre at the University of Alberta main campus, which is located in ᐊᒥᐢᑿᒌᐚᐢᑲᐦᐃᑲᐣ (Amiskwacîwâskahikan) on Treaty 6 territory, the territory of the Papaschase, and the homeland of the Métis Nation.


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